Is caffeine giving you IBS symptoms?
November 14, 2025Long Covid is a complex, multisystem condition that requires a personalised, functional medicine approach. Patients often have layered histories and complex clinical pictures that may feel overwhelming. This webinar offers a practical, safety-focused framework for navigating that complexity – starting with what to prioritise, and how to intervene 
without harm.
Blood
Impaired blood flow and disrupted oxygen delivery appear central to Long Covid pathophysiology. SARS-CoV-2 causes vascular inflammation and the formation of fibrinaloid microclots. Many of the other affected systems and pathways, including mitochondrial dysfunction, immune dysregulation, neuroinflammation, and even autonomic imbalance, may be downstream from oxygen depletion. Although clinical diagnostics for microclots are not yet widely accessible, this pathology should be considered in all cases. Therapeutic strategies show mixed results, and understanding risks, contraindications, and side-effect profiles is essential for safe implementation.
Guts
As functional medicine practitioners, we know that the gut is the core of health and connects with many other systems. SARS-CoV-2 infection of enterocytes can result in dysbiosis, inflammation, intestinal permeability, and immune dysregulation – indicating the gut as a strategic starting point. Targeting gastrointestinal health may offer a leverage point for immune regulation, neuroinflammation, histamine tolerance, and tryptophan–serotonin pathways. For many patients, the gut is the most effective place to begin modulation.
Ciara Wright PhD is an expert in Long Covid and the Positive Nutrition clinic specialises in advanced testing and analysis for patients with complex symptoms. Including advanced gut microbiome testing, blood clotting tests and endothelial damage, inflammation and immune exhaustion markers, organic acids metabolic testing and many others.
