DNA Blue Print Test

DNA Blueprint Genetic Test

DNA Blue Print Test

DNA Blueprint Genetic Test

€300

A very comprehensive analysis of underlying genetics related to metabolism, inflammation, detoxification, methylation, histamine and many more

Who can benefit from this test?

Your nutritionist may recommend this test if you have:

  • Strong family history of immune disorders or heart disease
  • Chronic illness
  • Histamine intolerance
  • Anyone interested in MTHFR, COMT, or a variety of underling pathways related to folate, B12 and methylation

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DNA Blue Print Test
 

Learn More about our DNA Blueprint

Swab (at-home)

The DNA Blueprint is a very comprehensive analysis of underlying genetics that can identify risk factors for disease, chronic conditions or weaknesses in metabolic or detoxification pathways. This only identifies relative risk – it does not represent a diagnosis or a definite outcome. Many people choose to look at underlying genetics to reduce their risk of developing conditions, or to safeguard or buffer against these risks with dietary, lifestyle or supplement interventions.

This test measures:

The number of genes analysed is very extensive, and covers the following areas:

  • Inflammation
  • Detoxification
  • Methylation
  • Oxidative stress

Systems

  • Collagen & joints
  • Bone health
  • Histamine overload
  • Glucose & insulin
  • Hormone balance
  • Mood & behaviour
  • Memory & brain health

Cardiovascular Health

  • Blood pressure
  • Vascular health
  • Blood clotting
  • Cholesterol

Energy

  • Adipogenesis
  • Exercise response
  • Energy expenditure
  • Weight gain & weight loss resistance
  • Pro-inflammatory fat
  • Appetite/Satiety/Intake

Activity

  • Injury
  • Power
  • Endurance
  • Recovery
  • Training response

Nutrients

  • Salt
  • Fatty acids
  • Vitamin B12
  • Vitamin D
  • Folate
  • Caffeine
  • Choline
  • Vitamin C
  • Gluten
  • Iron overload

Shauna had persistently low folate levels, with high MCV (a marker of red cell turnover) and sub-optimal B12 levels. She suffered from fatigue and low immune defences, and was constantly picking up infections. She was interested in her MTHFR status and her immune function.

Key findings [excerpt from test]

  • Shauna was a double homozygote for the MTHFR gene – which means she carried two changes (SNPs) in the DNA code for the enzyme that uses folate in the body. This pathway is essential for all new cell production given that it fuels new DNA synthesis. It is also essential for methylation in the body, a key detoxification and control for DNA transcription in the body i.e. what genes are turned on and off. Shauna needed to take methylfolate supplements to bypass this error in her genetics.
  • Shauna also had genetic issues with her MTR gene, which recycles B12 as part of the folate cycle. With this genetic issue, many people require higher amounts of B12 in order to properly fuel the folate cycle. Many people can suffer from functional B12 deficiency – i.e. the symptoms of low B12 even with normal B12 levels. Shauna would likely benefit from maintaining high normal serum levels of B12.
  • Shauna also had some SNPs or changes in her vitamin D pathway. She subsequently measured her serum vitamin D levels, which were low and her supplementation level was tailored accordingly.

Hormone DNA Risk Profile FAQ

How can DNA testing help me understand my hormones?
This analysis looks at specific genetic variations (SNPs) that influence how your body produces, metabolises, and clears hormones such as oestrogen, progesterone, testosterone, and DHEA. These genes do not determine your hormone levels directly, but they can influence how efficiently key pathways function — including hormone production, detoxification, and clearance. By understanding your genetic tendencies, we can better interpret patterns seen on hormone testing (such as the DUTCH Comprehensive Hormone Test) and tailor strategies to support optimal balance. This allows for a more personalised approach to hormone health, focusing not only on current levels, but also on underlying metabolic and enzymatic tendencies.
I feel well — can this test still be useful from a preventative or optimisation perspective?
Yes. Many individuals choose this test even in the absence of symptoms as part of a preventative or performance optimisation strategy. Genetic variations in oestrogen metabolism, methylation (e.g. MTHFR, COMT), and detoxification pathways can influence long-term hormonal balance and risk patterns, even before symptoms develop. Understanding these predispositions allows for early, targeted lifestyle and nutritional strategies to support optimal hormone metabolism and reduce future risk of imbalance.
I’ve already done genetic testing (e.g. Ancestry) — can I use that?
Yes. In most cases, raw DNA data from services such as AncestryDNA can be used for this analysis. We can extract and interpret relevant SNPs related to hormone metabolism, detoxification pathways, and methylation processes. This avoids the need for repeat genetic testing and allows us to build a functional report from existing data.
What is the difference between genetic risk and actual hormone levels?
Genetic findings reflect potential tendencies, not fixed outcomes. For example, a SNP may indicate reduced efficiency in oestrogen detoxification or methylation pathways, but this does not mean you currently have a hormone imbalance. Environmental factors such as diet, stress, gut health, toxin exposure, and sleep also play a major role in how these pathways function in real life. This is why genetic data is best interpreted alongside functional hormone testing (such as DUTCH) and clinical symptoms — to distinguish between predisposition and active dysfunction.