DUTCH Comprehensive Hormone Test

DUTCH Comprehensive Hormone Test

€440.00

The DUTCH test takes a very comprehensive look at hormones and their pathways, safe detoxification and the impact of long term stress. It also assesses several markers for nutrient deficiencies, antioxidants and neurotransmitters which play an important role in hormonal balance, PMS, pain, energy and mood balance.

Who can benefit from this test?

Your nutritionist may recommend this test if you have:

Hormonal conditions such as PCOS, fibroids and endometriosis
PMS or PMDD
Perimenopause, menopause, irregular cycles
Poor concentration and memory, insomnia, depression, loss of libido
Headaches, moods swings, anxiety, panic attacks, nervousness and/or irritability
Weight loss resistance, abdominal obesity
Chronic fatigue, low energy

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Learn More about our DUTCH Comprehensive Hormone test

What the test involves
Sample Test Report
Patient Experience Case Study

Urine sample (at-home)

The DUTCH test looks in detail at sex and stress hormones and their pathways. The information in this very comprehensive test allows your Nutritionist to personalise your hormonal protocol, identifying root cause imbalances and deficiencies that may be causing your symptoms.

This test measures:

Oestrogen – three forms
Oestrogen metabolites indicating how you detoxify oestrogen, and indicators of methylation, COMT and other genes involved in liver detoxification
Progesterone
Testosterone and metabolites of testosterone including the most active form 5αDHT
DHEA (a master hormone)
Melatonin
Cortisol (active, free form) and cortisone (inactive, free form) over four time points during the day
Cortisol and cortisone metabolites and total production
Markers of B6, B12, glutathione, biotin and oxidative stress
Markers of neuroinflammation, and dopamine and serotonin metabolism

Test options/ add-ons:

Cortisol awakening response (CAR) – in-depth detail about the initial rise of cortisol in the morning, critical to many functions and pathways in the body
Cycle Mapping – tracking the rise and fall of oestrogen and progesterone through the cycle to assess symptoms that occur at any stage
DUTCH for male hormones – similar to the DUTCH complete but with greater detail in the testosterone pathways

Goes well with:

Hormone DNA Risk Profile including liver detoxification, MTHFR and COMT genes

- Download Sample Report

Karina was experiencing extreme PMS symptoms including irritability, mood changes, acne, migraine and fatigue leading up to her period.

Her DUTCH test showed high levels of testosterone metabolites, high progesterone and a block in her oestrogen detoxification pathway due to poor methylation. She also had low morning cortisol and low overall cortisol production showing possible impacts of long term stress and low resilience.

Karina started on a herbal formula specially designed by our herbalist/ pharmacist to address higher testosterone levels. She also increased her levels of phytoestrogens in the diet to balance the very high progesterone. In addition, she started on a specific B vitamin formulation to support methylation and detoxification of oestrogen. Finally she also adapted her sleep and morning routines to support her circadian rhythm and improve rest and recovery overnight. The B vitamin formulation also contained stress/ adaptogen support.

After just one month on this protocol, her next cycle was much more manageable and her PMS symptoms reduced markedly over the coming months. After this, she was able to reduce her protocol to a maintenance plan.

Key findings:

Elevated levels of testosterone metabolites
High normal levels of progesterone, indicating ovulation
Relatively lower levels of oestradiol
Significantly reduced detoxification of 2-OH-oestradiol due to reduced methylation
Low morning cortisol levels and low overall cortisol output

DUTCH Test FAQ

How can this test help me with my fertility?

The DUTCH test gives a detailed look at your sex hormones and how your body processes them. It also tracks cortisol, your main stress hormone, throughout the day. For those trying to conceive, the test can reveal factors that may affect ovulation, progesterone levels after ovulation, how your body metabolizes oestrogen, and overall stress hormone balance — all of which play a key role in fertility.

How can this test help me with perimenopause/ menopause?

During perimenopause and menopause, hormone levels fluctuate, and symptoms like hot flashes, sleep disturbances, mood changes, and low energy often appear. The DUTCH test shows not only sex hormone levels but also how your body metabolises them and how stress hormones like cortisol are functioning throughout the day. Cortisol patterns can influence energy, sleep quality, stress resilience, and even hormone balance, so understanding both sex hormones and adrenal function gives a complete picture. With vast experience supporting patients through these transitions, we use DUTCH results to tailor protocols that reduce symptoms, support hormone metabolism, inform decision making around other treatments, and improve overall wellbeing during this stage of life.

I already did a hormonal blood test with my GP, how is this different?

Standard blood tests provide a single snapshot of basic hormone levels. The DUTCH test offers a more comprehensive view by: • Measuring many different types of testosterone and oestrogen, plus levels of DHEA which convert into other sex hormones – it is a much more comprehensive assessment of different types of hormones, all of which contribute to hormone signalling • Checking whether your body is processing oestrogen safely, instead of creating stronger, potentially harmful forms and highlighting how your body breaks down and removes hormones • Examining how your stress hormone (cortisol) changes throughout the day and measuring the sleep hormone melatonin • Additional markers of antioxidants, B vitamins, mood hormones – all of which relate to hormonal balance

Once I do this test, how will it help me feel better in the long run?

The DUTCH test helps uncover the root causes of hormonal imbalances that can contribute to fatigue, sleep problems, mood changes, reproductive issues, and stress-related symptoms. By identifying exactly what’s out of balance, we can create a personalised plan that addresses the underlying issues rather than just masking symptoms. No more guessing at supplements— our team uses decades of experience interpreting DUTCH results to design precise, individualised protocols.