Organic Acids Test (OAT)

Organic Acids Test (OAT)

€230.00

This test measures a wide number of markers of nutritional and metabolic health. It is most often used in complex conditions to rule in or out certain metabolic ‘blocks’ and mitochondrial issues.

Who can benefit from this test?

Your nutritionist may recommend this test if you have:

Complex conditions
Long covid, ME/CFS, chronic fatigue syndrome

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Urine test (at-home)

This is a simple urine test that can assess a wide number of nutritional and metabolic markers. Some complex conditions can be identified or ruled out with this test. Often it is pattern of these markers that can shed light on the root cause of complex metabolic or fatigue conditions. There are also a number of useful nutrient markers.

This test measures:

Energy production efficiency - lactate and glucose breakdown for energy and efficiency of using fats for fuel
Mitochondrial metabolites – evaluates for mitochondrial dysfunction
Markers of inflammation pathways, neuroinflammation and calming via the tryptophan pathway and gut bacteria via polyphenols
Neurotransmitter metabolites – evaluates for phenylalanine, tyrosine and tryptophan metabolism linked to neurotransmitter balance
Overnight cortisol measurement and aldosterone, an important hormone in blood pressure and blood volume which can be relevant in POTS or chronic fatigue
Useful markers of Candida and other bacteria in the gut (not as extensive as a stool test), oxalates
Nutritional markers of B vitamins, CoQ10, glutathione, folate cycle

- Download Test Instructions

Download Sample Report

Stacey had Long Covid for 18 months and was experiencing extreme fatigue and post-exertional malaise (PEM) amongst other symptoms. She carried out an organic acids test alongside a nutritional evaluation to see if she could support her energy metabolism, and rule out any further complex issues.

Her results did not identify any severe underlying mitochondrial disorders. Her neurotransmitter levels were normal, along with tryptophan and quinolinic/ kynurenic ratios which are a potential problem in some cases of Long Covid. There was some possible issues with her fat metabolism, which she needed to support with carnitine and B vitamins.

In conjunction with her other nutritional tests, this organic acids tests also highlighted a potential issue with her vitamin B6 pathway, given her low B6 marker and low phosphoric acid. This was a useful pathway for her to support and may have impacted her production of acetylcholine.

Key Findings [excerpt from test]:

No underlying complex mitochondrial issues
Poor fat metabolism which needed support to produce energy
Indicators of issue with vitamin B6 pathway

Organic Acids Test FAQ

How can this test help me feel better?

The Organic Acids Test (OAT) provides a functional snapshot of how your body is producing energy, detoxifying and metabolising nutrients. It can highlight imbalances in areas such as mitochondrial energy production, neurotransmitter metabolism, oxidative stress, microbial overgrowth, and key nutrient pathways that may contribute to fatigue, brain fog, mood changes, or poor stress tolerance. Rather than guessing which supplements or interventions might help, the OAT allows us to design a targeted, personalised plan based on your unique biochemistry.

I’ve already done a stool test, is this different?

Yes. Stool testing and the Organic Acids Test assess different aspects of gut and metabolic health. Stool tests focus primarily on what’s happening in the large intestine — including microbial balance, inflammation, and digestive function. The OAT, on the other hand, reflects how microbial activity and metabolism are influencing your body systemically. It gives insight into small intestinal and metabolic by-products, mitochondrial function, detoxification pathways, and nutrient utilisation — areas that stool testing does not assess. Used together or separately, these tests help us build a more complete clinical picture when needed.

I have already tested my micronutrients in blood, how is this different?

Blood tests measure circulating nutrient levels at a single point in time, which is useful for identifying deficiencies but doesn’t always reflect how well those nutrients are being absorbed, activated, or used inside cells. The OAT assesses functional markers that indicate nutrient demand and metabolic efficiency, often revealing subtle insufficiencies before they appear on blood work. This allows us to fine-tune supplementation, avoid unnecessary products, and prioritise what will actually support your health. If you’re supplementing but not seeing results — or want a more precise approach — the OAT may be helpful here.

I have Long Covid/ME/CFS – can this test help me?

For individuals with Long COVID or ME/CFS, symptoms such as fatigue, post-exertional malaise, cognitive dysfunction, and poor stress tolerance often reflect impaired energy metabolism, oxidative stress, and disrupted biochemical pathways. The OAT can provide insight into mitochondrial function, neurotransmitter balance, detoxification capacity, and microbial metabolites that may be contributing to symptom burden. While it is not diagnostic, it can help guide supportive, individualised strategies aimed at improving resilience and functional capacity over time. If you’re navigating complex, multi-system symptoms, the OAT can help inform a more nuanced plan. However, it may not be the first test to reach for so please talk to us about the best option for your unique circumstances.

I actually feel great; can this test still help with aspects like performance or supplement planning?

Yes. The OAT isn’t only for people who feel unwell. It’s also a powerful tool for optimising performance, cognitive function, stress resilience, and targeted supplementation. For high-performing individuals, the OAT can help identify early metabolic bottlenecks, unnecessary supplementation, or opportunities to support energy production and recovery more efficiently — before symptoms develop.